Concepedia

Romain Siegrist

RS

Statistics

Publications

14

Citations

503

H-Index

14

Active since

2003

Affiliations

Actelion (Switzerland)(Current)

University of Basel

Swiss Tropical and Public Health Institute

Roche (Switzerland)

Harvard University

Romain Siegrist is an author at Actelion (Switzerland) specializing in pharmacology, drug discovery, and medicinal chemistry.

Publications per year

2003–2017

14

Publications

14

The Natural Product Avrainvillamide Binds to the Oncoprotein Nucleophosmin

Jeremy E. Wulff, Romain Siegrist, Andrew G. Myers · Journal of the American Chemical Society · 2007 · 83 citations · Full text

, , +13

Discovery of a Potent, Selective T-type Calcium Channel Blocker as a Drug Candidate for the Treatment of Generalized Epilepsies

Olivier Bezençon, Bibia Heidmann, Romain Siegrist et al. · Journal of Medicinal Chemistry · 2017 · 61 citations · Full text

, , +9

Evidence for the Rapid Conversion of Stephacidin B into the Electrophilic Monomer Avrainvillamide in Cell Culture

Jeremy E. Wulff, Seth B. Herzon, Romain Siegrist et al. · Journal of the American Chemical Society · 2007 · 58 citations · Full text

, , +7

Novel in vivo active anti-malarials based on a hydroxy-ethyl-amine scaffold

Claire‐Lise Ciana, Romain Siegrist, Hamed Aissaoui et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 41 citations

, , +13

Structure–Activity Relationship, Biological, and Pharmacological Characterization of the Proline Sulfonamide ACT‐462206: a Potent, Brain‐Penetrant Dual Orexin 1/Orexin 2 Receptor Antagonist

Christoph Boss, Catherine Roch‐Brisbare, Michel A. Steiner et al. · ChemMedChem · 2014 · 40 citations

, , +15

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