Joseph M. Colacino

PTC124 targets genetic disorders caused by nonsense mutations

Ellen Welch, Elisabeth R. Barton, Jin Zhuo et al. · Nature · 2007 · 1.1K citations

Mendelian Disorder, Genetic Disorder, Genetics +4

<i>SMN2</i> splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy

Nikolai A. Naryshkin, Marla Weetall, Amal Dakka et al. · Science · 2014 · 517 citations

Genetics, Molecular Biology, Therapeutics +21

Toxicity of Antiviral Nucleoside Analogs and the Human Mitochondrial DNA Polymerase

Allison A. Johnson, Adrian S. Ray, Jeremiah W. Hanes et al. · Journal of Biological Chemistry · 2001 · 399 citations · Full text

Virucidal activity of hypericin against enveloped and non-enveloped DNA and RNA viruses

Joseph Tang, Joseph M. Colacino, STEPHEN H. LARSEN et al. · Antiviral Research · 1990 · 167 citations

Virology, Antimicrobial Chemotherapy, Rna Viruses +6

Fialuridine and its metabolites inhibit DNA polymerase gamma at sites of multiple adjacent analog incorporation, decrease mtDNA abundance, and cause mitochondrial structural defects in cultured hepatoblasts.

William Lewis, Eric S. Levine, B. Griniuvienė et al. · Proceedings of the National Academy of Sciences · 1996 · 163 citations · Full text

Single Adenosine, Molecular Biology, Dna Polymerase Gamma +18