Bernd Büttelmann

Fenobam: A Clinically Validated Nonbenzodiazepine Anxiolytic Is a Potent, Selective, and Noncompetitive mGlu5 Receptor Antagonist with Inverse Agonist Activity

Richard H. Porter, Georg Jaeschke, Will Spooren et al. · Journal of Pharmacology and Experimental Therapeutics · 2005 · 314 citations · Full text

CTEP: A Novel, Potent, Long-Acting, and Orally Bioavailable Metabotropic Glutamate Receptor 5 Inhibitor

Lothar Lindemann, Georg Jaeschke, Aubin Michalon et al. · Journal of Pharmacology and Experimental Therapeutics · 2011 · 121 citations

Metabotropic Glutamate Receptor 5 Negative Allosteric Modulators: Discovery of 2-Chloro-4-[1-(4-fluorophenyl)-2,5-dimethyl-1<i>H</i>-imidazol-4-ylethynyl]pyridine (Basimglurant, RO4917523), a Promising Novel Medicine for Psychiatric Diseases

Georg Jaeschke, Sabine Kolczewski, Will Spooren et al. · Journal of Medicinal Chemistry · 2015 · 63 citations · Full text

Psychotropic Medication, Psychopharmacology, Pharmacotherapy +19

Pharmacological Characterization of Ro 63-1908 (1-[2-(4-Hydroxy-phenoxy)-ethyl]-4-(4-methyl-benzyl)-piperidin-4-ol), a Novel Subtype-Selective N-Methyl-d-Aspartate Antagonist

R. Gill, Alexander Alanine, Anne Bourson et al. · Journal of Pharmacology and Experimental Therapeutics · 2002 · 50 citations

Discovery of the imidazo[1,5-a][1,2,4]-triazolo[1,5-d][1,4]benzodiazepine scaffold as a novel, potent and selective GABAA α5 inverse agonist series

Guido Achermann, Theresa M. Ballard, Francesca Blasco et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 28 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Medicine +6