Extracellular succinate hyperpolarizes M2 macrophages through SUCNR1/GPR91-mediated Gq signaling

Mette Trauelsen, Thomas K. Hiron, Da Lin, +9

Cell Reports

Succinate FunctionsImmunologyCellular PhysiologyInflammationSignaling Pathway +14

Digestion-ligation-only Hi-C is an efficient and cost-effective method for chromosome conformation capture

Da Lin, Ping Hong, Siheng Zhang, +9

Nature Genetics

Cost-effective MethodChromatinMolecular Biological MethodDigestion-ligation-only Hi-cGenetics +10

3D genome architecture coordinates trans and cis regulation of differentially expressed ear and tassel genes in maize

Yonghao Sun, Liang Dong, Ying Zhang, +9

Genome biology

Lipid-Induced Epigenomic Changes in Human Macrophages Identify a Coronary Artery Disease-Associated Variant that Regulates PPAP2B Expression through Altered C/EBP-Beta Binding

Michael E. Reschen, Kyle J. Gaulton, Da Lin, +4

PLoS Genetics

Vascular DiseaseImmunologyLipid-induced Epigenomic ChangesGenome-wide Association StudiesOxidative Stress +17

CoolBox: a flexible toolkit for visual analysis of genomics data

Weize Xu, Quan Zhong, Da Lin, +4

BMC Bioinformatics

HPV-CCDC106 integration alters local chromosome architecture and hijacks an enhancer by three-dimensional genome structure remodeling in cervical cancer

Canhui Cao, Ping Hong, Xingyu Huang, +24

Journal of genetics and genomics/Journal of Genetics and Genomics

Three-dimensional Genome StructureMolecular BiologyPathologyEpigeneticsCancer-associated Virus +15

NF-κB Regulates MICA Gene Transcription in Endothelial Cell through a Genetically Inhibitable Control Site

Da Lin, Hayley Lavender, Elizabeth J. Soilleux, +1

Journal of Biological Chemistry

Development and application of a recombination-based library versus library high- throughput yeast two-hybrid (RLL-Y2H) screening system

Fang� Yang, Yingying Lei, Meiling Zhou, +18

Nucleic Acids Research

EngineeringBiomolecular ToolMolecular BiologyScreening SystemMycobacterium Tuberculosis +19

Highly efficient and robust π-FISH rainbow for multiplexed in situ detection of diverse biomolecules

Yingfeng Tao, Xiaoliu Zhou, Leqiang Sun, +15

Nature Communications

Decoding the spatial chromatin organization and dynamic epigenetic landscapes of macrophage cells during differentiation and immune activation

Da Lin, Weize Xu, Ping Hong, +25

Nature Communications