Bin Jiang

A Diastereoselective Synthesis of 2,4-Disubstituted Piperidines:  Scaffolds for Drug Discovery

Paul S. Watson, Bin Jiang, Brian Scott · Organic Letters · 2000 · 312 citations

Combinatorial Chemistry, Medicinal Chemistry, Diversity Oriented Synthesis +12

Discovery of low nanomolar non-hydroxamate inhibitors of tumor necrosis factor-α converting enzyme (TACE)

James J.‐W. Duan, Lihua Chen, Zhonghui Lu et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 53 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Drug Targeting +9

Structure-based Discovery of Phenyl (3-Phenylpyrrolidin-3-yl)sulfones as Selective, Orally Active RORγt Inverse Agonists

James J.‐W. Duan, Zhonghui Lu, Bin Jiang et al. · ACS Medicinal Chemistry Letters · 2019 · 52 citations · Full text

Biologic-like In Vivo Efficacy with Small Molecule Inhibitors of TNFα Identified Using Scaffold Hopping and Structure-Based Drug Design Approaches

Hai‐Yun Xiao, Ning Li, James J.‐W. Duan et al. · Journal of Medicinal Chemistry · 2020 · 39 citations · Full text

Discovery of highly potent, selective, covalent inhibitors of JAK3

James Kempson, Damaso Ovalle, Junqing Guo et al. · Bioorganic & Medicinal Chemistry Letters · 2017 · 31 citations · Full text

Covalent Inhibitors, Medicinal Chemistry, Medicine +5