C. Michael Lin

Isolation and structure of the strong cell growth and tubulin inhibitor combretastatin A-4

George R. Pettit, Sheo B. Singh, Ernest Hamel et al. · Cellular and Molecular Life Sciences · 1989 · 789 citations

Life Sciences, Biochemistry, Cell Biology +11

2-Methoxyestradiol, an endogenous mammalian metabolite, inhibits tubulin polymerization by interacting at the colchicine site.

Robert J. D’Amato, C. Michael Lin, Evelyn Flynn et al. · Proceedings of the National Academy of Sciences · 1994 · 409 citations

Life Sciences, Chemical Biology, Pharmacology +16

Interactions of tubulin with potent natural and synthetic analogs of the antimitotic agent combretastatin: a structure-activity study.

C. Michael Lin, Sheo B. Singh, Ping S. Chu et al. · Molecular Pharmacology · 1988 · 282 citations

Medicine, Medicinal Chemistry, Pharmacology +16

The Binding Site Barrier Elicited by Tumor-Associated Fibroblasts Interferes Disposition of Nanoparticles in Stroma-Vessel Type Tumors

Lei Miao, Jay Newby, C. Michael Lin et al. · ACS Nano · 2016 · 212 citations

Medicine, Cell Biology, Oncology +17

Targeting Tumor-Associated Fibroblasts for Therapeutic Delivery in Desmoplastic Tumors

Lei Miao, Qi Liu, C. Michael Lin et al. · Cancer Research · 2016 · 210 citations · Full text

Pharmacy, Cancer Biology, Pharmaceutics +17