Nicholas J. Newcombe

Directed Dihydroxylation of Cyclic Allylic Alcohols and Trichloroacetamides Using OsO₄/TMEDA

Timothy J. Donohoe, Kevin Blades, Peter R. Moore et al. · The Journal of Organic Chemistry · 2002 · 138 citations

Cross-coupling Reaction, Bioorganic Chemistry, Biochemistry +9

AZD5438, a potent oral inhibitor of cyclin-dependent kinases 1, 2, and 9, leads to pharmacodynamic changes and potent antitumor effects in human tumor xenografts

Kate F. Byth, Andrew P. Thomas, Gareth Hughes et al. · Molecular Cancer Therapeutics · 2009 · 121 citations

The directed dihydroxylation of allylic alcohols

Timothy J. Donohoe, Peter R. Moore, Michael J. Waring et al. · Tetrahedron Letters · 1997 · 106 citations

Allylic Alcohols, Organic Chemistry, Stereoselective Synthesis +3

The total synthesis of (±)-gelsemine

Nicholas J. Newcombe, Fang Ya, R. J. VIJN et al. · Journal of the Chemical Society Chemical Communications · 1994 · 78 citations

Chemical Engineering, N. J. Newcombe, W. N. Speckamp +12

Discovery of Checkpoint Kinase Inhibitor (<i>S</i>)-5-(3-Fluorophenyl)-<i>N</i>-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide (AZD7762) by Structure-Based Design and Optimization of Thiophenecarboxamide Ureas

Vibha Oza, Susan Ashwell, Lynsie Almeida et al. · Journal of Medicinal Chemistry · 2012 · 67 citations · Full text

Drug Target, Molecular Biology, Chemical Biology +20