LEDGF (p75) promotes DNA-end resection and homologous recombination

Mads Daugaard, Annika Baude, Kasper Fugger, +10

Nature Structural & Molecular Biology

Cell BiologyRecombination DynamicMolecular BiologyDna-end Resection

Combination treatment of acute myeloid leukemia cells with DNMT and HDAC inhibitors: predominant synergistic gene downregulation associated with gene body demethylation

Nadja Blagitko‐Dorfs, Pascal Schlosser, Gabriele Greve, +6

Leukemia

Hematological MalignancyHdac InhibitorsMixed-phenotype Acute LeukemiaGene Body DemethylationMalignant Blood Disorder +9

Histone 3.3 hotspot mutations in conventional osteosarcomas: a comprehensive clinical and molecular characterization of six H3F3A mutated cases

Christian Koelsche, Daniel Schrimpf, Lars Tharun, +21

Clinical Sarcoma Research

Mutations of R882 change flanking sequence preferences of the DNA methyltransferase DNMT3A and cellular methylation patterns

Max Emperle, Sabrina Adam, Stefan Kunert, +6

Nucleic Acids Research

Histone ModificationsEpigenetic ChangeGeneticsDna MethylationAml Patients +21

The histone variant H3.3 G34W substitution in giant cell tumor of the bone link chromatin and RNA processing

Jinyeong Lim, Joo Hyun Park, Annika Baude, +12

Scientific Reports

Histone ModificationsEpigenetic ChangeGliomaEpigeneticsTumor Biology +20

Hepatoma-derived growth factor-related protein 2 promotes DNA repair by homologous recombination

Annika Baude, Tania Løve Aaes, Beibei Zhai, +5

Nucleic Acids Research

Replication Protein A2Cell ProliferationHdgfrp2-depleted CellsTumor BiologyPromotes Dna Repair +14

Globally altered epigenetic landscape and delayed osteogenic differentiation in H3.3-G34W-mutant giant cell tumor of bone

Pavlo Lutsik, Annika Baude, Daniela Mancarella, +30

Nature Communications

Small Molecule Inhibitors Targeting HIV‐1 Reverse Transcriptase Dimerization

Dina Grohmann, Valentina Corradi, Mira Elbasyouny, +5

ChemBioChem

Molecular DockingMedicinal ChemistryRt Dimer EquilibriumBiochemistryRt Subunits P51 +12

PRC2 loss amplifies Ras signaling in cancer

Annika Baude, Anders M. Lindroth, Christoph Plass

Nature Genetics

Tumor BiologyMedicineTumor SuppressorCancer GeneticsCancer Biology +2

Swedish Local Government

Annika Baude

American Political Science Review