Lars Tharun

Codon-specific translation reprogramming promotes resistance to targeted therapy

Francesca Rapino, Sylvain Delaunay, Florian Rambow et al. · Nature · 2018 · 255 citations

Engineering, Novel Therapy, Clinical Translation +5

HER-2 amplification is highly homogenous in gastric cancer

Andreas H. Marx, Lars Tharun, Johanna Muth et al. · Human Pathology · 2009 · 206 citations

Tumor Biology, Gastrointestinal Oncology, Medicine +5

Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer

Sylvain Delaunay, Francesca Rapino, Lars Tharun et al. · The Journal of Experimental Medicine · 2016 · 176 citations · Full text

A Synergistic Interaction between Chk1- and MK2 Inhibitors in KRAS-Mutant Cancer

Felix Dietlein, Bastian Kalb, Mladen Jokić et al. · Cell · 2015 · 125 citations

Tumor Biology, Radiation Oncology, Synergistic Interaction +10

Characterization of tumor-associated T-lymphocyte subsets and immune checkpoint molecules in head and neck squamous cell carcinoma

Axel Lechner, Hans Schlößer, Sacha I. Rothschild et al. · Oncotarget · 2017 · 125 citations · Full text

Immune Checkpoint Molecules, Immunology, Immune Regulation +21