Sabrina Adam

Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms

Linfeng Gao, Max Emperle, Yiran Guo et al. · Nature Communications · 2020 · 181 citations · Full text

DNA sequence-dependent activity and base flipping mechanisms of DNMT1 regulate genome-wide DNA methylation

Sabrina Adam, Hiwot Anteneh, Maximilian Hornisch et al. · Nature Communications · 2020 · 80 citations · Full text

Mutations of R882 change flanking sequence preferences of the DNA methyltransferase DNMT3A and cellular methylation patterns

Max Emperle, Sabrina Adam, Stefan Kunert et al. · Nucleic Acids Research · 2019 · 70 citations · Full text

Histone Modifications, Epigenetic Change, Genetics +23

Engineering of Effector Domains for Targeted DNA Methylation with Reduced Off-Target Effects

Daniel Tobias Hofacker, Julian Broche, Laura Laistner et al. · International Journal of Molecular Sciences · 2020 · 62 citations · Full text

Histone Modifications, Reduced Off-target Effects, Epigenetic Change +18

DNA methyltransferase DNMT3A forms interaction networks with the CpG site and flanking sequence elements for efficient methylation

Michael Dukatz, Marianna Dittrich, Elias Stahl et al. · Journal of Biological Chemistry · 2022 · 32 citations · Full text