Michael G. Malkowski

Antitumor activity of SCH 66336, an orally bioavailable tricyclic inhibitor of farnesyl protein transferase, in human tumor xenograft models and wap-ras transgenic mice.

Ming Liu, Matthew Bryant, Jianping Chen et al. · PubMed · 1998 · 309 citations

Sch 66336, Chemoprevention Strategy, Farnesyl Protein Transferase +15

The Productive Conformation of Arachidonic Acid Bound to Prostaglandin Synthase

Michael G. Malkowski, Stephan L. Ginell, William L. Smith et al. · Science · 2000 · 298 citations

Crystal Structure of Aspirin-Acetylated Human Cyclooxygenase-2: Insight into the Formation of Products with Reversed Stereochemistry

Michael J. Lucido, Benjamin J. Orlando, Alex J. Vecchio et al. · Biochemistry · 2016 · 228 citations · Full text

Crystal Structure, Medicinal Chemistry, Pharmaceutical Chemistry +14

Substrate-selective Inhibition of Cyclooxygeanse-2 by Fenamic Acid Derivatives Is Dependent on Peroxide Tone

Benjamin J. Orlando, Michael G. Malkowski · Journal of Biological Chemistry · 2016 · 221 citations · Full text

Biochemistry, Medicine, Lipid Peroxidation +7

Prostaglandin Endoperoxide H Synthase-1

Elizabeth D. Thuresson, Karen M. Lakkides, Caroline Jill Rieke et al. · Journal of Biological Chemistry · 2001 · 191 citations · Full text