Alex J. Vecchio

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Publications

Citations

1.6K

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Active since

1977

Affiliations

University at Buffalo, State University of New York(Current)

University of Nebraska–Lincoln

Hauptman-Woodward Medical Research Institute

Cornell University

École Polytechnique Fédérale de Lausanne

Alex J. Vecchio is an author at University at Buffalo, State University of New York specializing in life sciences, biochemistry, and structural biology.

ORCID

Publications per year

1977–2025

Publications

Crystal Structure of Aspirin-Acetylated Human Cyclooxygenase-2: Insight into the Formation of Products with Reversed Stereochemistry

Michael J. Lucido, Benjamin J. Orlando, Alex J. Vecchio et al. · Biochemistry · 2016 · 239 citations · Full text

Life Sciences, Biochemistry, Pharmacology +13

Structural Basis of Fatty Acid Substrate Binding to Cyclooxygenase-2

Alex J. Vecchio, Danielle M. Simmons, Michael G. Malkowski · Journal of Biological Chemistry · 2010 · 164 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

One-shot design of functional protein binders with BindCraft

Martin Pačesa, Lennart Nickel, Christian Schellhaas et al. · Nature · 2025 · 158 citations · Full text

Life Sciences, Biotechnology, Molecular Biology +16

Computational design of soluble and functional membrane protein analogues

Casper A. Goverde, Martin Pačesa, Nicolas Goldbach et al. · Nature · 2024 · 124 citations · Full text

Life Sciences, Biochemistry, Computational Design +17

Human Cyclooxygenase-2 Is a Sequence Homodimer That Functions as a Conformational Heterodimer

Liang Dong, Alex J. Vecchio, Narayan P. Sharma et al. · Journal of Biological Chemistry · 2011 · 115 citations · Full text

Life Sciences, Biochemistry, Pharmacology +15

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