Concepedia

Alex J. Vecchio

AJ

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Publications

24

Citations

1.4K

H-Index

18

Active since

1977

Affiliations

University at Buffalo, State University of New York(Current)

Hauptman-Woodward Medical Research Institute

University of Nebraska–Lincoln

Cornell University

École Polytechnique Fédérale de Lausanne

Alex J. Vecchio is an author at University at Buffalo, State University of New York specializing in biochemistry, natural sciences, and health sciences.

ORCID

Top concepts

Publications per year

1977–2025

24

Publications

24

Crystal Structure of Aspirin-Acetylated Human Cyclooxygenase-2: Insight into the Formation of Products with Reversed Stereochemistry

Michael J. Lucido, Benjamin J. Orlando, Alex J. Vecchio et al. · Biochemistry · 2016 · 228 citations · Full text

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Structural Basis of Fatty Acid Substrate Binding to Cyclooxygenase-2

Alex J. Vecchio, Danielle M. Simmons, Michael G. Malkowski · Journal of Biological Chemistry · 2010 · 162 citations · Full text

Human Cyclooxygenase-2 Is a Sequence Homodimer That Functions as a Conformational Heterodimer

Liang Dong, Alex J. Vecchio, Narayan Prasad Sharma et al. · Journal of Biological Chemistry · 2011 · 112 citations · Full text

, , +16

Computational design of soluble and functional membrane protein analogues

Casper A. Goverde, Martin Pačesa, Nicolas Goldbach et al. · Nature · 2024 · 97 citations · Full text

BindCraft: one-shot design of functional protein binders

Martin Pačesa, Lennart Nickel, Christian Schellhaas et al. · 2024 · 95 citations · Full text

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