Leonardo Brunetti

Lack of the architectural factor HMGA1 causes insulin resistance and diabetes in humans and mice

Daniela Foti, Eusebio Chiefari, Monica Fedele et al. · Nature Medicine · 2005 · 223 citations

Insulin Resistance, Metabolic Syndrome, Insulin Signaling +10

Human diabetes associated with defects in nuclear regulatory proteins for the insulin receptor gene.

Antonio Brunetti, Leonardo Brunetti, Daniela Foti et al. · Journal of Clinical Investigation · 1996 · 42 citations · Full text

Genetics, Insulin Receptor Gene, Insulin Receptor +16

Structure-based design of novel donepezil-like hybrids for a multi-target approach to the therapy of Alzheimer's disease

Leonardo Brunetti, Rosalba Leuci, Antonio Carrieri et al. · European Journal of Medicinal Chemistry · 2022 · 38 citations · Full text

Alzheimer's Disease, Polymer-drug Conjugate, Medicine +9

Novel Rivastigmine Derivatives as Promising Multi-Target Compounds for Potential Treatment of Alzheimer’s Disease

David Vicente-Zurdo, Noelia Rosales‐Conrado, María Eugenia León‐González et al. · Biomedicines · 2022 · 36 citations · Full text

Importance of Biometals as Targets in Medicinal Chemistry: An Overview about the Role of Zinc (II) Chelating Agents

Rosalba Leuci, Leonardo Brunetti, Antonio Laghezza et al. · Applied Sciences · 2020 · 32 citations · Full text

Medicinal Chemistry, Neurodegenerative Diseases, Biochemistry +13