Atsuo T. Sasaki

Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer

Arkaitz Carracedo, Li Ma, Julie Teruya‐Feldstein et al. · Journal of Clinical Investigation · 2008 · 1.4K citations · Full text

Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses

Dimitrios Anastasiou, George Poulogiannis, John M. Asara et al. · Science · 2011 · 1.2K citations · Full text

Lipid Peroxidation, Cell Death, Metabolic Remodeling +19

R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m6A/MYC/CEBPA Signaling

Rui Su, Lei Dong, Chenying Li et al. · Cell · 2017 · 1.2K citations · Full text

Tumor Biology, Medicine, Tumor Suppressor +3

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

Jason W. Locasale, Alexandra Grassian, Tamar Melman et al. · Nature Genetics · 2011 · 1.1K citations · Full text

Biochemistry, Phosphoglycerate Dehydrogenase, Catabolism +4

Spred is a Sprouty-related suppressor of Ras signalling

Toru Wakioka, Atsuo T. Sasaki, Reiko Kato et al. · Nature · 2001 · 440 citations

Signal Transduction, Sprouty-related Suppressor, Gene Regulation +4