Atsuo T. Sasaki

Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer

Arkaitz Carracedo, Li Ma, Julie Teruya‐Feldstein et al. · Journal of Clinical Investigation · 2008 · 1.4K citations · Full text

Medicine, Oncology, Pharmacology +17

R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m6A/MYC/CEBPA Signaling

Rui Su, Lei Dong, Chenying Li et al. · Cell · 2017 · 1.2K citations · Full text

Medicine, Oncology, Pharmacology +10

Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses

Dimitrios Anastasiou, George Poulogiannis, John M. Asara et al. · Science · 2011 · 1.2K citations · Full text

Life Sciences, Biochemistry, Oncology +17

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

Jason W. Locasale, Alexandra Grassian, Tamar Melman et al. · Nature Genetics · 2011 · 1.1K citations · Full text

Life Sciences, Cancer Biology, Molecular Biology +13

Spred is a Sprouty-related suppressor of Ras signalling

Toru Wakioka, Atsuo T. Sasaki, Reiko Kato et al. · Nature · 2001 · 445 citations

Life Sciences, Genetics, Molecular Biology +11