Brian J. Smith

Differential Targeting of Prosurvival Bcl-2 Proteins by Their BH3-Only Ligands Allows Complementary Apoptotic Function

Lin Chen, Simon N. Willis, Andrew H. Wei et al. · Molecular Cell · 2005 · 1.8K citations · Full text

Medicine, Apoptosis, Immunology +7

Bax Crystal Structures Reveal How BH3 Domains Activate Bax and Nucleate Its Oligomerization to Induce Apoptosis

Peter E. Czabotar, Dana Westphal, Grant Dewson et al. · Cell · 2013 · 563 citations · Full text

The B30.2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1β production

Jae Jin Chae, Geryl Wood, Seth L. Masters et al. · Proceedings of the National Academy of Sciences · 2006 · 544 citations · Full text

B30.2 Domain, Immune Regulation, Immunology +23

A newly discovered protein export machine in malaria parasites

Tania F. de Koning‐Ward, Paul R. Gilson, Justin A. Boddey et al. · Nature · 2009 · 511 citations · Full text

Protein Export Machine, Natural Sciences, Medicine +5

Structural insights into the degradation of Mcl-1 induced by BH3 domains

Peter E. Czabotar, Erinna F. Lee, Mark F. van Delft et al. · Proceedings of the National Academy of Sciences · 2007 · 437 citations · Full text

Protein Assembly, Apoptosis, Molecular Biology +18