Kindlin-3 is essential for integrin activation and platelet aggregation

Markus Moser, Bernhard Nieswandt, Siegfried Ussar, +2

Nature Medicine

ThrombopoiesisThrombosisBlood PlateletHematologyVascular Biology +6

SILAC Mouse for Quantitative Proteomics Uncovers Kindlin-3 as an Essential Factor for Red Blood Cell Function

Marcus Krüger, Markus Moser, Siegfried Ussar, +7

Cell

Knockout MouseEssential FactorAutoimmune DiseaseMedicineHematology +6

Interactions between Gut Microbiota, Host Genetics and Diet Modulate the Predisposition to Obesity and Metabolic Syndrome

Siegfried Ussar, Nicholas W. Griffin, Olivier Bézy, +7

Cell Metabolism

ObesityNutritionMetabolic SyndromeDysbiosisBody Composition +13

Kindlin-2 controls bidirectional signaling of integrins

Eloi Montañez, Siegfried Ussar, Martina Schifferer, +4

Genes & Development

Cell AdhesionCytoskeletonCellular PhysiologyEndocytic PathwayMatrix Biology +14

Leukocyte adhesion deficiency-III is caused by mutations in KINDLIN3 affecting integrin activation

Lena Svensson, Kimberley Howarth, Alison McDowall, +8

Nature Medicine

Autoimmune DiseaseCell AdhesionLeukocyte Adhesion Deficiency-iiiHematologyImmunology +11

Lessons on Conditional Gene Targeting in Mouse Adipose Tissue

Kevin Y. Lee, Steven J. Russell, Siegfried Ussar, +9

Diabetes

Sirt3 Regulates Metabolic Flexibility of Skeletal Muscle Through Reversible Enzymatic Deacetylation

Enxuan Jing, Brian T. O’Neill, Matthew J. Rardin, +9

Diabetes

Sirt3 ExpressionEnergy MetabolismMuscle FunctionMitochondrial FunctionBiochemistry +13

The Kindlins: Subcellular localization and expression during murine development

Siegfried Ussar, Hao‐Ven Wang, Stefan Linder, +2

Experimental Cell Research

Murine DevelopmentDevelopmental BiologyDevelopmental GeneticsMorphogenesisCellular Biochemistry +3

Diet, Genetics, and the Gut Microbiome Drive Dynamic Changes in Plasma Metabolites

Shiho Fujisaka, Julián Ávila-Pacheco, Marion Soto, +9

Cell Reports

NutritionDysbiosisGut BacteriaHost-microbe InteractionsMetabolomic Profiling +19

Loss of Kindlin-1 Causes Skin Atrophy and Lethal Neonatal Intestinal Epithelial Dysfunction

Siegfried Ussar, Markus Moser, Moritz Widmaier, +4

PLoS Genetics

AllergyAutoimmune DiseaseDisease MechanismPathogenesisImmunology +10