Ian J. Restall

Inhibition of the Mitochondrial Protease ClpP as a Therapeutic Strategy for Human Acute Myeloid Leukemia

Alicia M. Cole, Zezhou Wang, Étienne Coyaud et al. · Cancer Cell · 2015 · 340 citations · Full text

Hematological Malignancy, Mitochondrial Function, Mitochondrial Protease Clpp +10

Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells

Graham MacLeod, Danielle Bozek, Nishani Rajakulendran et al. · Cell Reports · 2019 · 237 citations · Full text

Engineering, Genetics, Glioma +17

PRMT5 inhibition disrupts splicing and stemness in glioblastoma

Patty Sachamitr, Jolene Caifeng Ho, Felipe E. Ciamponi et al. · Nature Communications · 2021 · 205 citations · Full text

PTEN loss represses glioblastoma tumor initiating cell differentiation via inactivation of Lgl1

Alexander Gont, Jennifer Hanson, Sylvie J. Lavictoire et al. · Oncotarget · 2013 · 34 citations · Full text

Brain Tumor Stem Cell Dependence on Glutaminase Reveals a Metabolic Vulnerability through the Amino Acid Deprivation Response Pathway

Ian J. Restall, Orsolya Cseh, Laura M. Richards et al. · Cancer Research · 2020 · 31 citations · Full text

Chemoprevention Strategy, Neurochemical Biomarkers, Metabolic Remodeling +20