Graham MacLeod

High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities

Traver Hart, Megha Chandrashekhar, Michael Aregger et al. · Cell · 2015 · 1.7K citations · Full text

Genotype-specific Cancer Liabilities, Engineering, Genetics +9

High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies

Ji‐Young Youn, Wade H. Dunham, Seo Jung Hong et al. · Molecular Cell · 2018 · 796 citations

Subcellular Organization, Medicine, Natural Sciences +12

Functional Enhancers Shape Extrachromosomal Oncogene Amplifications

Andrew R. Morton, Nergiz Doğan, Zachary Faber et al. · Cell · 2019 · 351 citations · Full text

Chromatin, Genetics, Genomic Mechanism +5

Gradient of Developmental and Injury Response transcriptional states defines functional vulnerabilities underpinning glioblastoma heterogeneity

Laura M. Richards, Owen Whitley, Graham MacLeod et al. · Nature Cancer · 2021 · 306 citations

Neuro-oncology, Transcriptional Regulation, Lineage Plasticity +10

Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer

Léo Aubert, Neethi Nandagopal, Zachary Steinhart et al. · Nature Communications · 2020 · 304 citations · Full text