Danielle Bozek

Gradient of Developmental and Injury Response transcriptional states defines functional vulnerabilities underpinning glioblastoma heterogeneity

Laura M. Richards, Owen Whitley, Graham MacLeod et al. · Nature Cancer · 2021 · 306 citations

Neuro-oncology, Transcriptional Regulation, Lineage Plasticity +10

Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells

Graham MacLeod, Danielle Bozek, Nishani Rajakulendran et al. · Cell Reports · 2019 · 237 citations · Full text

Engineering, Genetics, Glioma +17

BI-907828, a novel potent MDM2 inhibitor, inhibits glioblastoma brain tumor stem cells in vitro and prolongs survival in orthotopic xenograft mouse models

Xiaoguang Hao, Ravinder Kaur Bahia, Orsolya Cseh et al. · Neuro-Oncology · 2022 · 31 citations · Full text

Epigenetic and molecular coordination between HDAC2 and SMAD3-SKI regulates essential brain tumour stem cell characteristics

Ravinder Kaur Bahia, Xiaoguang Hao, Rozina Hassam et al. · Nature Communications · 2023 · 22 citations · Full text

Live-Cell Imaging Assays to Study Glioblastoma Brain Tumor Stem Cell Migration and Invasion

Ian J. Restall, Danielle Bozek, Charles Chesnelong et al. · Journal of Visualized Experiments · 2018 · 11 citations · Full text