Ruth Matesanz

Arylthioindole Inhibitors of Tubulin Polymerization. 3. Biological Evaluation, Structure−Activity Relationships and Molecular Modeling Studies

Giuseppe La Regina, Michael Edler, Andrea Brancale et al. · Journal of Medicinal Chemistry · 2007 · 211 citations

Cyclostreptin binds covalently to microtubule pores and lumenal taxoid binding sites

Rubén M. Buey, Enrique Calvo, Isabel Barasoaı́n et al. · Nature Chemical Biology · 2007 · 151 citations

Signal Transduction, Biochemistry, Natural Sciences +8

Zampanolide, a Potent New Microtubule-Stabilizing Agent, Covalently Reacts with the Taxane Luminal Site in Tubulin α,β-Heterodimers and Microtubules

Jessica J. Field, Benet Pera, Enrique Calvo et al. · Chemistry & Biology · 2012 · 83 citations · Full text

Biochemistry, Natural Sciences, Taxane Luminal Site +6

Triazolopyrimidines Are Microtubule-Stabilizing Agents that Bind the Vinca Inhibitor Site of Tubulin

Gonzalo Sáez-Calvo, Ashwani Sharma, Francisco de Asís Balaguer et al. · Cell chemical biology · 2017 · 80 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Inhibitory Activity +10

Optimization of Taxane Binding to Microtubules: Binding Affinity Dissection and Incremental Construction of a High-Affinity Analog of Paclitaxel

Ruth Matesanz, Isabel Barasoaı́n, Chun‐Gang Yang et al. · Chemistry & Biology · 2008 · 77 citations

Taxane Binding, Medicinal Chemistry, High-affinity Analog +11