Cyclostreptin binds covalently to microtubule pores and lumenal taxoid binding sites

References

Page 1

	Year	Citations
Promotion of microtubule assembly in vitro by taxol Peter B. Schiff, Jane Fant, Susan Band Horwitz Nature MicropropagationCell CultureCytoskeletonMicrotubule AssemblyTissue Culture	1979	3.6K
Structure of the αβ tubulin dimer by electron crystallography Eva Nogales, Sharon G. Wolf, Kenneth H. Downing Nature Crystal Structureαβ Tubulin DimerProtein X-ray CrystallographyMolecular BiologyStructure Determination	1998	2K
High-Resolution Model of the Microtubule Eva Nogales, Michael Whittaker, Ronald A. Milligan, Cell Biophysical ModelingPattern FormationPhysicsMicroscopyNatural Sciences	1999	1.2K
Colchicine-binding protein of mammalian brain and its relation to microtubules Richard C. Weisenberg, Gary G. Broisy, Edwin W. Taylor Biochemistry Altmetric Attention ScoreMolecular BiologyCytoskeletonClinical NeuroscienceNeurotransmission	1968	1.1K
Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations. Mary Ann Jordan, Robert Toso, Douglas Thrower, Proceedings of the National Academy of Sciences Nm TaxolCell DeathCell CultureCell ProliferationCytoskeleton	1993	1.1K
Paclitaxel-resistant Human Ovarian Cancer Cells Have Mutant β-Tubulins That Exhibit Impaired Paclitaxel-driven Polymerization Paraskevi Giannakakou, Dan L. Sackett, Yoon‐Koo Kang, Journal of Biological Chemistry	1997	681
Taxol binds to polymerized tubulin in vitro Jerome Parness, SB Horwitz The Journal of Cell Biology	1981	619
Analysis of numerical methods for computer simulation of kinetic processes: Development of KINSIM—A flexible, portable system Bruce A. Barshop, Richard F. Wrenn, Carl Frieden Analytical Biochemistry Numerical AnalysisEngineeringProcess Simulation ModelMechanical EngineeringNumerical Simulation	1983	595
A common pharmacophore for epothilone and taxanes: Molecular basis for drug resistance conferred by tubulin mutations in human cancer cells Paraskevi Giannakakou, Rick Gussio, Eva Nogales, Proceedings of the National Academy of Sciences Tubulin BindingDrug TargetMolecular BiologyTubulin Mutant CellsChemical Biology	2000	475
Structure of Human Methionine Aminopeptidase-2 Complexed with Fumagillin Shenping Liu, Joanne Widom, Christopher W. Kemp, Science Drug TargetProtein AssemblyBiomolecular Structure PredictionMedicinal FungiChemical Biology	1998	437

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