Rachelle Gent

Adrenal C11-oxy C21 steroids contribute to the C11-oxy C19 steroid pool via the backdoor pathway in the biosynthesis and metabolism of 21-deoxycortisol and 21-deoxycortisone

Lise Barnard, Rachelle Gent, Desmaré van Rooyen et al. · The Journal of Steroid Biochemistry and Molecular Biology · 2017 · 41 citations

Adrenal Gland, Oxysterol, Biochemistry +10

The 11β-hydroxysteroid dehydrogenase isoforms: pivotal catalytic activities yield potent C11-oxy C19 steroids with 11βHSD2 favouring 11-ketotestosterone, 11-ketoandrostenedione and 11-ketoprogesterone biosynthesis

Rachelle Gent, Therina du Toit, Liezl M. Bloem et al. · The Journal of Steroid Biochemistry and Molecular Biology · 2019 · 41 citations

Biosynthesis, Aldehyde Dehydrogenase, Biochemistry +6

The in vitro metabolism of 11β-hydroxyprogesterone and 11-ketoprogesterone to 11-ketodihydrotestosterone in the backdoor pathway

Desmaré van Rooyen, Rachelle Gent, Lise Barnard et al. · The Journal of Steroid Biochemistry and Molecular Biology · 2017 · 35 citations

Biochemistry, Endocrine Mechanism, Medicine +6

Non-invasive assessment of fecal glucocorticoid, progesterone, and androgen metabolites and microbiome in free-ranging southern white rhinoceros (Ceratotherium simum simum) in South Africa

Kadden Kothmann, Amanda Jons, Brendan Wilhelmi et al. · General and Comparative Endocrinology · 2022 · 12 citations

Fecal Glucocorticoid, Non-invasive Assessment, Mammalogy +4

11α-Hydroxyprogesterone, a potent 11β-hydroxysteroid dehydrogenase inhibitor, is metabolised by steroid-5α-reductase and cytochrome P450 17α-hydroxylase/17,20-lyase to produce C11α-derivatives of 21-deoxycortisol and 11-hydroxyandrostenedione in vitro

Rachelle Gent, Therina du Toit, Amanda C. Swart · The Journal of Steroid Biochemistry and Molecular Biology · 2019 · 10 citations