Liezl M. Bloem

11β-Hydroxydihydrotestosterone and 11-ketodihydrotestosterone, novel C19 steroids with androgenic activity: A putative role in castration resistant prostate cancer?

Karl‐Heinz Storbeck, Liezl M. Bloem, Donita Africander et al. · Molecular and Cellular Endocrinology · 2013 · 193 citations

Urology, Novel C19 Steroids, Androgenic Activity +9

11β-Hydroxyandrostenedione, the product of androstenedione metabolism in the adrenal, is metabolized in LNCaP cells by 5α-reductase yielding 11β-hydroxy-5α-androstanedione

Amanda C. Swart, Lindie Schloms, Karl‐Heinz Storbeck et al. · The Journal of Steroid Biochemistry and Molecular Biology · 2013 · 119 citations

Androstenedione Metabolism, Adrenal Gland, Biosynthesis +12

Profiling adrenal 11β-hydroxyandrostenedione metabolites in prostate cancer cells, tissue and plasma: UPC2-MS/MS quantification of 11β-hydroxytestosterone, 11keto-testosterone and 11keto-dihydrotestosterone

Therina du Toit, Liezl M. Bloem, Jonathan L. Quanson et al. · The Journal of Steroid Biochemistry and Molecular Biology · 2016 · 66 citations

Urology, Adrenal 11β-Hydroxyandrostenedione, Medicine +11

The 11β-hydroxysteroid dehydrogenase isoforms: pivotal catalytic activities yield potent C11-oxy C19 steroids with 11βHSD2 favouring 11-ketotestosterone, 11-ketoandrostenedione and 11-ketoprogesterone biosynthesis

Rachelle Gent, Therina du Toit, Liezl M. Bloem et al. · The Journal of Steroid Biochemistry and Molecular Biology · 2019 · 41 citations

Biosynthesis, Aldehyde Dehydrogenase, Biochemistry +6

What’s in a whisker? High-throughput analysis of twenty-eight C19 and C21 steroids in mammalian whiskers by ultra-performance convergence chromatography-tandem mass spectrometry

Nico Lübcker, Liezl M. Bloem, Therina du Toit et al. · Journal of Chromatography B · 2020 · 16 citations

C21 Steroids, Biochemistry, Medicine +10