Amanda C. Swart

11β-Hydroxydihydrotestosterone and 11-ketodihydrotestosterone, novel C19 steroids with androgenic activity: A putative role in castration resistant prostate cancer?

Karl‐Heinz Storbeck, Liezl M. Bloem, Donita Africander et al. · Molecular and Cellular Endocrinology · 2013 · 193 citations

Urology, Novel C19 Steroids, Androgenic Activity +9

11β-Hydroxyandrostenedione, the product of androstenedione metabolism in the adrenal, is metabolized in LNCaP cells by 5α-reductase yielding 11β-hydroxy-5α-androstanedione

Amanda C. Swart, Lindie Schloms, Karl‐Heinz Storbeck et al. · The Journal of Steroid Biochemistry and Molecular Biology · 2013 · 119 citations

Androstenedione Metabolism, Adrenal Gland, Biosynthesis +12

Progesterone 16 alpha-hydroxylase activity is catalyzed by human cytochrome P450 17 alpha-hydroxylase.

Pieter Swart, Amanda C. Swart, Matti Waterman et al. · The Journal of Clinical Endocrinology & Metabolism · 1993 · 101 citations

Molecular Pharmacology, Human Cytochrome P450c17, Biochemistry +12

The influence of Aspalathus linearis (Rooibos) and dihydrochalcones on adrenal steroidogenesis: Quantification of steroid intermediates and end products in H295R cells

Lindie Schloms, Karl‐Heinz Storbeck, Pieter Swart et al. · The Journal of Steroid Biochemistry and Molecular Biology · 2011 · 88 citations

Adrenal Gland, Aspalathus Linearis, Oxysterol +10

Profiling adrenal 11β-hydroxyandrostenedione metabolites in prostate cancer cells, tissue and plasma: UPC2-MS/MS quantification of 11β-hydroxytestosterone, 11keto-testosterone and 11keto-dihydrotestosterone

Therina du Toit, Liezl M. Bloem, Jonathan L. Quanson et al. · The Journal of Steroid Biochemistry and Molecular Biology · 2016 · 66 citations

Urology, Adrenal 11β-Hydroxyandrostenedione, Medicine +11