Diabetes primes neutrophils to undergo NETosis, which impairs wound healing

Siu Ling Wong, Mélanie Demers, Kimberly Martinod, +5

Nature Medicine

InflammationGranulocyteDiabetesImmunologyChronic Inflammation +6

Maresins: novel macrophage mediators with potent antiinflammatory and proresolving actions

Charles N. Serhan, Rong Yang, Kimberly Martinod, +5

The Journal of Experimental Medicine

Neutrophil extracellular traps promote deep vein thrombosis in mice

Alexander Brill, Tobias A. Fuchs, A.S. Savchenko, +5

Journal of Thrombosis and Haemostasis

InflammationThrombosisThrombopoiesisNeutrophil Extracellular TrapsGranulocyte +6

Cancers predispose neutrophils to release extracellular DNA traps that contribute to cancer-associated thrombosis

Mélanie Demers, Daniela S. Krause, Daphne Schatzberg, +5

Proceedings of the National Academy of Sciences

Hematological MalignancyExtracellular Dna TrapsMalignant DiseaseMedicineGranulocyte +13

Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation

Huw D. Lewis, John Liddle, Jim Coote, +30

Nature Chemical Biology

P-selectin promotes neutrophil extracellular trap formation in mice

Julia Etulain, Kimberly Martinod, Siu Ling Wong, +3

Blood

Neutrophil histone modification by peptidylarginine deiminase 4 is critical for deep vein thrombosis in mice

Kimberly Martinod, Mélanie Demers, Tobias A. Fuchs, +6

Proceedings of the National Academy of Sciences

Chromatin DecondensationDeep Vein ThrombosisImmunologyPathologyEpigenetics +19

Increased neutrophil extracellular trap formation promotes thrombosis in myeloproliferative neoplasms

Ofir Wolach, Rob S. Sellar, Kimberly Martinod, +21

Science Translational Medicine

Elevated Levels of Circulating DNA and Chromatin Are Independently Associated With Severe Coronary Atherosclerosis and a Prothrombotic State

Julian Ilcheff Borissoff, Ivo A. Joosen, Mathijs O. Versteylen, +10

Arteriosclerosis Thrombosis and Vascular Biology

Extracellular DNA traps are associated with the pathogenesis of TRALI in humans and mice

Grace M. Thomas, Carla Carbó, Brian R. Curtis, +9

Blood