Ahmad Z. Wardak

Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis

Emma J. Petrie, Jarrod J. Sandow, Annette V. Jacobsen et al. · Nature Communications · 2018 · 189 citations · Full text

Evolutionary divergence of the necroptosis effector MLKL

Maria C. Tanzer, I Matti, Joanne M. Hildebrand et al. · Cell Death and Differentiation · 2016 · 126 citations · Full text

Evolutionary Divergence, Pathogenesis, Apoptosis +4

Mutation to Bax beyond the BH3 Domain Disrupts Interactions with Pro-survival Proteins and Promotes Apoptosis

Peter E. Czabotar, Erinna F. Lee, Geoff Thompson et al. · Journal of Biological Chemistry · 2011 · 118 citations · Full text

Protein Function, Signaling Pathway, Cell Regulation +14

Parkin inhibits BAK and BAX apoptotic function by distinct mechanisms during mitophagy

Jonathan P. Bernardini, Jason M. Brouwer, Iris K. L. Tan et al. · The EMBO Journal · 2018 · 107 citations · Full text

Distinct Mechanisms, Mitophagy, Cell Autophagy +9

CD52 glycan binds the proinflammatory B box of HMGB1 to engage the Siglec-10 receptor and suppress human T cell function

Esther Bandala‐Sanchez, Naiara G. Bediaga, Ethan D. Goddard‐Borger et al. · Proceedings of the National Academy of Sciences · 2018 · 82 citations · Full text

Proinflammatory B Box, Adaptive Immune System, Immunology +23