José M. Andreu

Assembly of purified GDP-tubulin into microtubules induced by taxol and taxotere: Reversibility, ligand stoichiometry, and competition

José M. Andreu · Biochemistry · 1993 · 416 citations

Low-Resolution Structures of Proteins in Solution Retrieved from X-Ray Scattering with a Genetic Algorithm

Pablo Chacón, Federico Morán, E. Pantos et al. · Biophysical Journal · 1998 · 284 citations · Full text

X-ray Crystallography, Low-resolution Structures, Protein Folding +12

A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs

A.E. Prota, Katja Bargsten, J. Fernando Dı́az et al. · Proceedings of the National Academy of Sciences · 2014 · 272 citations · Full text

The Microtubule Stabilizing Agent Laulimalide Does Not Bind in the Taxoid Site, Kills Cells Resistant to Paclitaxel and Epothilones, and May Not Require Its Epoxide Moiety for Activity

Donald E. Pryor, Aurora O’Brate, Geoffrey Bilcer et al. · Biochemistry · 2002 · 253 citations

Microtubule Interactions with Chemically Diverse Stabilizing Agents: Thermodynamics of Binding to the Paclitaxel Site Predicts Cytotoxicity

Rubén M. Buey, Isabel Barasoaı́n, Evelyn M. Jackson et al. · Chemistry & Biology · 2005 · 225 citations · Full text

Medicinal Chemistry, Microtubule Interactions, Biochemistry +12