José M. Andreu

Assembly of purified GDP-tubulin into microtubules induced by taxol and taxotere: Reversibility, ligand stoichiometry, and competition

José M. Andreu · Biochemistry · 1993 · 416 citations

Life Sciences, Biochemistry, Cell Biology +9

Low-Resolution Structures of Proteins in Solution Retrieved from X-Ray Scattering with a Genetic Algorithm

Pablo Chacón, Federico Morán, E. Pantos et al. · Biophysical Journal · 1998 · 288 citations · Full text

Life Sciences, Biochemistry, Bioinformatics +16

A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs

A.E. Prota, Katja Bargsten, J. Fernando Dı́az et al. · Proceedings of the National Academy of Sciences · 2014 · 279 citations · Full text

Life Sciences, Medicinal Chemistry, Oncology +17

The Microtubule Stabilizing Agent Laulimalide Does Not Bind in the Taxoid Site, Kills Cells Resistant to Paclitaxel and Epothilones, and May Not Require Its Epoxide Moiety for Activity

Donald E. Pryor, Aurora O’Brate, Geoffrey Bilcer et al. · Biochemistry · 2002 · 255 citations

Medicine, Oncology, Pharmacology +17

Microtubule Interactions with Chemically Diverse Stabilizing Agents: Thermodynamics of Binding to the Paclitaxel Site Predicts Cytotoxicity

Rubén M. Buey, Isabel Barasoaı́n, Evelyn M. Jackson et al. · Chemistry & Biology · 2005 · 227 citations · Full text

Medicine, Oncology, Pharmacology +16