Aurora O’Brate

Paclitaxel Resistance in Non–Small-Cell Lung Cancer Associated With Beta-Tubulin Gene Mutations

Mariano Monzó, Rafael Rosell, José Javier Sánchez et al. · Journal of Clinical Oncology · 1999 · 315 citations

The Microtubule Stabilizing Agent Laulimalide Does Not Bind in the Taxoid Site, Kills Cells Resistant to Paclitaxel and Epothilones, and May Not Require Its Epoxide Moiety for Activity

Donald E. Pryor, Aurora O’Brate, Geoffrey Bilcer et al. · Biochemistry · 2002 · 253 citations

Enhanced microtubule-dependent trafficking and p53 nuclear accumulation by suppression of microtubule dynamics

Paraskevi Giannakakou, Michel Y. Nakano, K. C. Nicolaou et al. · Proceedings of the National Academy of Sciences · 2002 · 202 citations · Full text

Apoptosis, Molecular Biology, Cell Death +19

Chemistry and Biology of Diazonamide A:  Second Total Synthesis and Biological Investigations

K. C. Nicolaou, Junliang Hao, Mali V. Reddy et al. · Journal of the American Chemical Society · 2004 · 169 citations

Interaction of Epothilone Analogs with the Paclitaxel Binding Site

Rubén M. Buey, J. Fernando Dı́az, José M. Andreu et al. · Chemistry & Biology · 2004 · 117 citations · Full text

Medicinal Chemistry, Drug Target, Medicine +5