Christina Spry

Pantothenamides Are Potent, On-Target Inhibitors of Plasmodium falciparum Growth When Serum Pantetheinase Is Inactivated

Christina Spry, Cristiano Macuamule, Zhiyang Lin et al. · PLoS ONE · 2013 · 102 citations · Full text

A Class of Pantothenic Acid Analogs Inhibits <i>Plasmodium falciparum</i> Pantothenate Kinase and Represses the Proliferation of Malaria Parasites

Christina Spry, Christina L. L. Chai, Kiaran Kirk et al. · Antimicrobial Agents and Chemotherapy · 2005 · 59 citations · Full text

Biochemistry, First Step, Medicine +10

Structural Modification of Pantothenamides Counteracts Degradation by Pantetheinase and Improves Antiplasmodial Activity

Marianne de Villiers, Cristiano Macuamule, Christina Spry et al. · ACS Medicinal Chemistry Letters · 2013 · 57 citations · Full text

Improves Antiplasmodial Activity, Potent Analogues, Pantothenamide Analogues +15

Mutations in the pantothenate kinase of Plasmodium falciparum confer diverse sensitivity profiles to antiplasmodial pantothenate analogues

Erick T. Tjhin, Christina Spry, Alan L. Sewell et al. · PLoS Pathogens · 2018 · 36 citations · Full text

Antiplasmodial Pantothenate Analogues, Parasitic Protozoa, Medicine +13

The Human Malaria Parasite Plasmodium falciparum Is Not Dependent on Host Coenzyme A Biosynthesis

Christina Spry, Kevin J. Saliba · Journal of Biological Chemistry · 2009 · 33 citations · Full text