Erick T. Tjhin

A Pantetheinase-Resistant Pantothenamide with Potent, On-Target, and Selective Antiplasmodial Activity

Cristiano Macuamule, Erick T. Tjhin, Collins E. Jana et al. · Antimicrobial Agents and Chemotherapy · 2015 · 38 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Mutations in the pantothenate kinase of Plasmodium falciparum confer diverse sensitivity profiles to antiplasmodial pantothenate analogues

Erick T. Tjhin, Christina Spry, Alan L. Sewell et al. · PLoS Pathogens · 2018 · 37 citations · Full text

Veterinary Medicine, Pharmacology, Comparative Genomics +16

Studies with the <i>Plasmodium falciparum</i> hexokinase reveal that PfHT limits the rate of glucose entry into glycolysis

Erick T. Tjhin, Henry M. Staines, Donelly A. van Schalkwyk et al. · FEBS Letters · 2013 · 28 citations

Life Sciences, Biochemistry, Molecular Biology +17

Substrate-mediated regulation of the arginine transporter of Toxoplasma gondii

Esther Rajendran, Morgan Clark, Cibelly Goulart et al. · PLoS Pathogens · 2021 · 25 citations · Full text

Life Sciences, Biology, Microbiology +15

Toward a Stable and Potent Coenzyme A-Targeting Antiplasmodial Agent: Structure–Activity Relationship Studies of <i>N</i>-Phenethyl-α-methyl-pantothenamide

Christina Spry, Leanne Barnard, Michélle Kok et al. · ACS Infectious Diseases · 2020 · 23 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15