Fabrice Vergne

Discovery of thiadiazoles as a novel structural class of potent and selective PDE7 inhibitors. Part 1: Design, synthesis and structure–activity relationship studies

Fabrice Vergne, Patrick Bernardelli, Edwige Lorthiois et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 57 citations · Full text

Novel Structural Class, Medicinal Chemistry, Medicine +9

Spiroquinazolinones as novel, potent, and selective PDE7 inhibitors. Part 1

Edwige Lorthiois, Patrick Bernardelli, Fabrice Vergne et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 50 citations · Full text

Medicinal Chemistry, Medicine, Rational Drug Design +7

Spiroquinazolinones as novel, potent, and selective PDE7 inhibitors. Part 2: Optimization of 5,8-disubstituted derivatives

Patrick Bernardelli, Edwige Lorthiois, Fabrice Vergne et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 38 citations · Full text

Medicinal Chemistry, Medicine, 5,8-Disubstituted Derivatives +7

Discovery of thiadiazoles as a novel structural class of potent and selective PDE7 inhibitors. Part 2: Metabolism-directed optimization studies towards orally bioavailable derivatives

Fabrice Vergne, Patrick Bernardelli, Edwige Lorthiois et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 36 citations

Novel Structural Class, Medicinal Chemistry, Biochemistry +8

Synthesis of 1-amino-1-(aminomethyl)cyclopropane and its monobenzamides

Fabrice Vergne, David J. Aitken, Henri Philippe Husson · The Journal of Organic Chemistry · 1992 · 27 citations

Molecular Sciences, Bioorganic Chemistry, Heterocyclic +10