Gesine Behrens

Roquin Suppresses the PI3K-mTOR Signaling Pathway to Inhibit T Helper Cell Differentiation and Conversion of Treg to Tfr Cells

Katharina Essig, Desheng Hu, Joao C. Guimaraes et al. · Immunity · 2017 · 180 citations · Full text

Pi3k-mtor Signaling Pathway, Signal Transduction, Signaling Pathway +10

A human immune dysregulation syndrome characterized by severe hyperinflammation with a homozygous nonsense Roquin-1 mutation

Simon J. Tavernier, Vicki Athanasopoulos, Patrick Verloo et al. · Nature Communications · 2019 · 62 citations · Full text

Roquin targets mRNAs in a 3′-UTR-specific manner by different modes of regulation

Katharina Essig, Nina Kronbeck, Joao C. Guimaraes et al. · Nature Communications · 2018 · 60 citations · Full text

Disrupting Roquin-1 interaction with Regnase-1 induces autoimmunity and enhances antitumor responses

Gesine Behrens, Stephanie L. Edelmann, Timsse Raj et al. · Nature Immunology · 2021 · 60 citations · Full text

Roquin-1 Interaction, Autoimmune Disease, Signaling Pathway +12

Defining the RBPome of primary T helper cells to elucidate higher-order Roquin-mediated mRNA regulation

Kai P. Hoefig, Alexander Reim, Christian Gallus et al. · Nature Communications · 2021 · 42 citations · Full text