Chromosome instability is common in human cleavage-stage embryos

Evelyne Vanneste, Thierry Voet, Cédric Le Caignec, +12

Nature Medicine

ChromatinChromosome InstabilityChromosome DynamicsDevelopmental BiologyCytogenetics +5

Fusion of NUP214 to ABL1 on amplified episomes in T-cell acute lymphoblastic leukemia

Carlos Graux, Jan Cools, Cindy Melotte, +20

Nature Genetics

Hematological MalignancyTumor BiologyMedicineMixed-phenotype Acute LeukemiaMolecular Biology +5

What next for preimplantation genetic screening? High mitotic chromosome instability rate provides the biological basis for the low success rate

Evelyne Vanneste, Thierry Voet, Cindy Melotte, +7

Human Reproduction

Genetic TestingFertilityCytogeneticsGeneticsPreimplantation Genetic Testing +24

Molecular Karyotyping: Array CGH Quality Criteria for Constitutional Genetic Diagnosis

Joris Vermeesch, Cindy Melotte, Guy Froyen, +11

Journal of Histochemistry & Cytochemistry

Array CghGenetic TestingCytogeneticsGeneticsComparative Genomic Hybridization +20

Concurrent Whole-Genome Haplotyping and Copy-Number Profiling of Single Cells

Masoud Zamani Esteki, Eftychia Dimitriadou, Ligia Mateiu, +14

The American Journal of Human Genetics

Functional GenomicsSingle Cell SequencingMedicineGeneticsComputational Genomics +9

Preimplantation genetic screening for aneuploidy of embryos after in vitro fertilization in women aged at least 35 years: a prospective randomized trial

Sophie Debrock, Cindy Melotte, Carl Spiessens, +7

Fertility and Sterility

InfertilityDevelopmental BiologyFertilityPreimplantation Genetic ScreeningPrenatal Genetic Testing +13

Deletion of VCX-A due to NAHR plays a major role in the occurrence of mental retardation in patients with X-linked ichthyosis

Hilde Van Esch, Karen Hollanders, Liesbeth Badisco, +7

Human Molecular Genetics

ChromatinMendelian DisorderMajor RoleGenetic DisorderGenetics +13

Autosomal-Dominant Microtia Linked to Five Tandem Copies of a Copy-Number-Variable Region at Chromosome 4p16

Irina Balikova, Kevin Martens, Cindy Melotte, +13

The American Journal of Human Genetics

ChromatinGenome InstabilityAutosomal-dominant Microtia LinkedCytogeneticsGenetic Disorder +12

Breakage-fusion-bridge cycles leading to inv dup del occur in human cleavage stage embryos

Thierry Voet, Evelyne Vanneste, Niels van der Aa, +9

Human Mutation

GeneticsGenomicsReproductive BiologyEpigeneticsEmbryology +14

The <i>C20orf133</i> gene is disrupted in a patient with Kabuki syndrome

Nicole Maas, Tom Van de Putte, Cindy Melotte, +8

Journal of Medical Genetics