Eeva Sommer

Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III phosphoinositide 3-kinase

Ružica Bago, Nazma Malik, Michael J. Munson et al. · Biochemical Journal · 2014 · 306 citations · Full text

Class Iii, Proteinlipid Interaction, Molecular Biology +18

Protor-1 is required for efficient mTORC2-mediated activation of SGK1 in the kidney

Laura R. Pearce, Eeva Sommer, Kei Sakamoto et al. · Biochemical Journal · 2011 · 177 citations · Full text

Cancer Biology, Cellular Physiology, Tumor Biology +18

Elevated SGK1 predicts resistance of breast cancer cells to Akt inhibitors

Eeva Sommer, Hannah Dry, Darren A.E. Cross et al. · Biochemical Journal · 2013 · 160 citations · Full text

Breast Oncology, Akt Protein Kinase, Cancer Biology +16

PRR5L degradation promotes mTORC2-mediated PKC-δ phosphorylation and cell migration downstream of Gα12

Xiaoqing Gan, Jiyong Wang, Chen Wang et al. · Nature Cell Biology · 2012 · 154 citations · Full text

Signal Transduction, Cell Regulation, Molecular Pathway +13

Characterization of GSK2334470, a novel and highly specific inhibitor of PDK1

Ayaz Najafov, Eeva Sommer, Jeffrey M. Axten et al. · Biochemical Journal · 2010 · 132 citations · Full text

Specific Inhibitor, Pdk1 Target, Cancer Biology +18