Joel Rubin

Inhibitors of the inducible microsomal prostaglandin E2 synthase (mPGES-1) derived from MK-886

Denis Riendeau, Renée Aspiotis, Diane Ethier et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 142 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +5

Substituted phenanthrene imidazoles as potent, selective, and orally active mPGES-1 inhibitors

Bernard Côté, Louise Boulet, Christine Brideau et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 128 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +11

Inhibition of the Activation of Multiple Serine Proteases with a Cathepsin C Inhibitor Requires Sustained Exposure to Prevent Pro-enzyme Processing

Nathalie Méthot, Joel Rubin, Daniel Guay et al. · Journal of Biological Chemistry · 2007 · 77 citations · Full text

Discovery of disubstituted phenanthrene imidazoles as potent, selective and orally active mPGES-1 inhibitors

André Giroux, Louise Boulet, Christine Brideau et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 61 citations · Full text

Medicinal Chemistry, Disubstituted Phenanthrene Imidazoles, Biochemistry +11

In Vivo Inhibition of Serine Protease Processing Requires a High Fractional Inhibition of Cathepsin C

Nathalie Méthot, Daniel Guay, Joel Rubin et al. · Molecular Pharmacology · 2008 · 53 citations