Renée Aspiotis

Caspase inhibitors improve survival in sepsis: a critical role of the lymphocyte

Richard S. Hotchkiss, K. Chang, Paul E. Swanson et al. · Nature Immunology · 2000 · 524 citations

Inflammation, Critical Role, Immunology +11

Inhibitors of the inducible microsomal prostaglandin E2 synthase (mPGES-1) derived from MK-886

Denis Riendeau, Renée Aspiotis, Diane Ethier et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 142 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +5

Reducing the Peptidyl Features of Caspase-3 Inhibitors:  A Structural Analysis

Joseph W. Becker, J. Rotonda, S.M. Soisson et al. · Journal of Medicinal Chemistry · 2004 · 86 citations · Full text

Diastereoselective Intermolecular [4 + 3] Cycloadditions via an Extended Transition State:  A Route to Enantiomerically Enriched Cycloadducts

Mark Lautens, Renée Aspiotis, John Colucci · Journal of the American Chemical Society · 1996 · 53 citations

Molecular Sciences, Engineering, Heterocyclic +12

Discovery of MK-0952, a selective PDE4 inhibitor for the treatment of long-term memory loss and mild cognitive impairment

Michel Gallant, Renée Aspiotis, Stephen H. Day et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 43 citations · Full text

Alzheimer's Disease, Medicine, Dementia +10