Tongmei Li

Potent and selective inhibitors of Akt kinases slow the progress of tumors <i>in vivo</i>

Yan Luo, Alexander R. Shoemaker, Xuesong Liu et al. · Molecular Cancer Therapeutics · 2005 · 244 citations · Full text

Akt Kinases, Signal Transduction Pathways, Medicine +14

Synthesis and SAR of indazole-pyridine based protein kinase B/Akt inhibitors

Keith W. Woods, John P. Fischer, Akiyo Claiborne et al. · Bioorganic & Medicinal Chemistry · 2006 · 81 citations

Medicinal Chemistry, Medicine, Rational Drug Design +7

Benzimidazolones and indoles as non-thiol farnesyltransferase inhibitors based on tipifarnib scaffold: synthesis and activity

Qun Li, Tongmei Li, Keith W. Woods et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 73 citations · Full text

Medicinal Chemistry, Natural Product Synthesis, Bioorganic Chemistry +10

Syntheses of Potent, Selective, and Orally Bioavailable Indazole-Pyridine Series of Protein Kinase B/Akt Inhibitors with Reduced Hypotension

Gui‐Dong Zhu, Viraj B. Gandhi, Jianchun Gong et al. · Journal of Medicinal Chemistry · 2007 · 62 citations · Full text

Pharmaceutical Science, Protein Kinase B/akt, Pharmacotherapy +16

Synthesis and structure–activity relationship of 3,4′-bispyridinylethylenes: Discovery of a potent 3-isoquinolinylpyridine inhibitor of protein kinase B (PKB/Akt) for the treatment of cancer

Qun Li, Keith W. Woods, Sheela A. Thomas et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 38 citations · Full text

Structure–activity Relationship, Medicinal Chemistry, Biochemistry +8