Chai Ping Lee

Discovery of Kinase Spectrum Selective Macrocycle (16<i>E</i>)-14-Methyl-20-oxa-5,7,14,26-tetraazatetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8(27),9,11,16,21,23-decaene (SB1317/TG02), a Potent Inhibitor of Cyclin Dependent Kinases (CDKs), Janus Kinase 2 (JAK2), and Fms-like Tyrosine Kinase-3 (FLT3) for the Treatment of Cancer

Anthony D. William, Angeline C.-H. Lee, Kee Chuan Goh et al. · Journal of Medicinal Chemistry · 2011 · 100 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Discovery of the Macrocycle (9<i>E</i>)-15-(2-(Pyrrolidin-1-yl)ethoxy)-7,12,25-trioxa-19,21,24-triaza-tetracyclo[18.3.1.1(2,5).1(14,18)]hexacosa-1(24),2,4,9,14(26),15,17,20,22-nonaene (SB1578), a Potent Inhibitor of Janus Kinase 2/Fms-LikeTyrosine Kinase-3 (JAK2/FLT3) for the Treatment of Rheumatoid Arthritis

Anthony D. William, Angeline C.-H. Lee, Anders Poulsen et al. · Journal of Medicinal Chemistry · 2012 · 52 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

2-Anilino-4-aryl-8H-purine derivatives as inhibitors of PDK1

Stéphanie Blanchard, Chang Kai Soh, Chai Ping Lee et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 11 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10