Sonal Rajyaguru

The Hepatitis C Virus Replicon Presents a Higher Barrier to Resistance to Nucleoside Analogs than to Nonnucleoside Polymerase or Protease Inhibitors

Matthew F. McCown, Sonal Rajyaguru, Sophie Le Pogam et al. · Antimicrobial Agents and Chemotherapy · 2008 · 164 citations · Full text

Hcv Replicon, Hepatitis C Virus, Immunology +19

Existence of hepatitis C virus NS5B variants naturally resistant to non-nucleoside, but not to nucleoside, polymerase inhibitors among untreated patients

Sophie Le Pogam, A. Seshaadri, Alan Kosaka et al. · Journal of Antimicrobial Chemotherapy · 2008 · 134 citations

Selection and Characterization of Replicon Variants Dually Resistant to Thumb- and Palm-Binding Nonnucleoside Polymerase Inhibitors of the Hepatitis C Virus

Sophie Le Pogam, Hyunsoon Kang, Seth F. Harris et al. · Journal of Virology · 2006 · 129 citations · Full text

Thumb Site Inhibitor, Biochemistry, Hepatitis C Virus +15

In vitro selected Con1 subgenomic replicons resistant to 2′-C-Methyl-Cytidine or to R1479 show lack of cross resistance

Sophie Le Pogam, Wen-Rong Jiang, Vincent Lévêque et al. · Virology · 2006 · 128 citations

Cross Resistance, Molecular Research, Con1 Subgenomic Replicons +10

GT-1a or GT-1b Subtype-Specific Resistance Profiles for Hepatitis C Virus Inhibitors Telaprevir and HCV-796

Matthew F. McCown, Sonal Rajyaguru, Simran Kular et al. · Antimicrobial Agents and Chemotherapy · 2009 · 119 citations · Full text

Viral Replication, Hepatitis C, Viral Hepatitis +15