Fernando W. Sehgelmeble

Sulfonimidamides as Sulfonamides Bioisosteres: Rational Evaluation through Synthetic, in Vitro, and in Vivo Studies with γ‐Secretase Inhibitors

Fernando W. Sehgelmeble, Juliette Janson, Colin Ray et al. · ChemMedChem · 2012 · 86 citations

Pharmaceutical Science, Secondary Metabolite, Chemical Biology +17

A Novel β-Directing Fructofuranosyl Donor Concept. Stereospecific Synthesis of Sucrose

Stefan Oscarson, Fernando W. Sehgelmeble · Journal of the American Chemical Society · 2000 · 63 citations

Anomeric Ch2oh Group, Biosynthesis, Bioorganic Chemistry +14

Synthesis and arylation of unprotected sulfonimidamides

Matías Funes Maldonado, Fernando W. Sehgelmeble, Fanny Bjarnemark et al. · Tetrahedron · 2012 · 59 citations

Organic Chemistry, Unprotected Sulfonimidamides, Synthetic Chemistry +1

Aminoimidazoles as BACE-1 inhibitors: The challenge to achieve in vivo brain efficacy

Britt‐Marie Swahn, Jörg Holenz, Jacob Kihlström et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 48 citations · Full text

Medicine, Pharmacology, Bace-1 Inhibitors +10

Core Refinement toward Permeable β-Secretase (BACE-1) Inhibitors with Low hERG Activity

Tobias Ginman, Jenny Viklund, Jonas Malmström et al. · Journal of Medicinal Chemistry · 2012 · 40 citations · Full text

Combinatorial Chemistry, Protein Secretion, Drug Target +22