Tobias Ginman

New Aminoimidazoles as β-Secretase (BACE-1) Inhibitors Showing Amyloid-β (Aβ) Lowering in Brain

Ylva Gravenfors, Jenny Viklund, Jan Blid et al. · Journal of Medicinal Chemistry · 2012 · 65 citations · Full text

New Aminoimidazoles, Neurochemical Biomarkers, Pharmaceutical Chemistry +23

Novel Class of Potent and Cellularly Active Inhibitors Devalidates MTH1 as Broad-Spectrum Cancer Target

Manuel Ellermann, Ashley Eheim, Fredrik Rahm et al. · ACS Chemical Biology · 2017 · 57 citations · Full text

Broad-spectrum Cancer Target, Cancer Dependency, Present Bay-707 +12

Core Refinement toward Permeable β-Secretase (BACE-1) Inhibitors with Low hERG Activity

Tobias Ginman, Jenny Viklund, Jonas Malmström et al. · Journal of Medicinal Chemistry · 2012 · 40 citations · Full text

Combinatorial Chemistry, Protein Secretion, Drug Target +22

Creation of a Novel Class of Potent and Selective MutT Homologue 1 (MTH1) Inhibitors Using Fragment-Based Screening and Structure-Based Drug Design

Fredrik Rahm, Jenny Viklund, L. Tresaugues et al. · Journal of Medicinal Chemistry · 2018 · 33 citations · Full text

Pharmacokinetic profile of N-acetylcysteine amide and its main metabolite in mice using new analytical method

Rui He, Wenyi Zheng, Tobias Ginman et al. · European Journal of Pharmaceutical Sciences · 2019 · 32 citations

Medicinal Chemistry, Pharmaceutical Science, N-acetylcysteine Amide +13