Ylva Gravenfors

Ultralarge Virtual Screening Identifies SARS-CoV-2 Main Protease Inhibitors with Broad-Spectrum Activity against Coronaviruses

Andreas Luttens, Hjalmar Gullberg, Eldar Abdurakhmanov et al. · Journal of the American Chemical Society · 2022 · 234 citations · Full text

Viral Diagnostics, Immunology, Molecular Biology +18

New Aminoimidazoles as β-Secretase (BACE-1) Inhibitors Showing Amyloid-β (Aβ) Lowering in Brain

Ylva Gravenfors, Jenny Viklund, Jan Blid et al. · Journal of Medicinal Chemistry · 2012 · 65 citations · Full text

New Aminoimidazoles, Neurochemical Biomarkers, Pharmaceutical Chemistry +23

Core Refinement toward Permeable β-Secretase (BACE-1) Inhibitors with Low hERG Activity

Tobias Ginman, Jenny Viklund, Jonas Malmström et al. · Journal of Medicinal Chemistry · 2012 · 40 citations · Full text

Combinatorial Chemistry, Protein Secretion, Drug Target +22

The Oncolytic Efficacy and in Vivo Pharmacokinetics of [2-(4-Chlorophenyl)quinolin-4-yl](piperidine-2-yl)methanol (Vacquinol-1) Are Governed by Distinct Stereochemical Features

Lars G.J. Hammarström, Robert K. Harmel, Mikael Granath et al. · Journal of Medicinal Chemistry · 2016 · 17 citations · Full text

Pharmaceutical Science, Active Isomers, Oncolytic Efficacy +19

Discovery of novel pyrrolopyridazine scaffolds as transient receptor potential vanilloid (TRPV1) antagonists

Ismet Dorange, Rickard Forsblom, István Macsári et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 14 citations · Full text

Medicinal Chemistry, Biochemistry, Natural Sciences +7