Jörg Holenz

Synthesis and Biological Evaluation of the 1-Arylpyrazole Class of σ₁ Receptor Antagonists: Identification of 4-{2-[5-Methyl-1-(naphthalen-2-yl)-1<i>H</i>-pyrazol-3-yloxy]ethyl}morpholine (S1RA, E-52862)

José Luis Dı́az, Rosa Cuberes, Joana Berrocal et al. · Journal of Medicinal Chemistry · 2012 · 129 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Naphthylisoquinoline alkaloids against malaria: evaluation of the curative potentials of dioncophylline C and dioncopeltine A against Plasmodium berghei in vivo

Guido François, G. Timperman, W M Eling et al. · Antimicrobial Agents and Chemotherapy · 1997 · 129 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Design and Synthesis of β-Site Amyloid Precursor Protein Cleaving Enzyme (BACE1) Inhibitors with in Vivo Brain Reduction of β-Amyloid Peptides

Britt‐Marie Swahn, Karin Kolmodin, Sofia Karlström et al. · Journal of Medicinal Chemistry · 2012 · 100 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Medicinal Chemistry Driven Approaches Toward Novel and Selective Serotonin 5-HT₆Receptor Ligands

Jörg Holenz, Ramon Mercè, José Luis Dı́az et al. · Journal of Medicinal Chemistry · 2004 · 96 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Sulfonimidamides as Sulfonamides Bioisosteres: Rational Evaluation through Synthetic, in Vitro, and in Vivo Studies with γ‐Secretase Inhibitors

Fernando W. Sehgelmeble, Juliette Janson, Colin Ray et al. · ChemMedChem · 2012 · 92 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17