Susruta Majumdar

Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor

Tao Che, Susruta Majumdar, Saheem A. Zaidi et al. · Cell · 2018 · 362 citations · Full text

Kappa Opioid Receptor, Molecular Pharmacology, Functional Selectivity +9

Mitragynine/Corynantheidine Pseudoindoxyls As Opioid Analgesics with Mu Agonism and Delta Antagonism, Which Do Not Recruit β-Arrestin-2

András Váradi, Gina F. Marrone, Travis C. Palmer et al. · Journal of Medicinal Chemistry · 2016 · 297 citations · Full text

Pain Medicine, Mitragynine/corynantheidine Pseudoindoxyls, Pharmacotherapy +20

Synthetic and Receptor Signaling Explorations of the <i>Mitragyna</i> Alkaloids: Mitragynine as an Atypical Molecular Framework for Opioid Receptor Modulators

Andrew C. Kruegel, Madalee M. Gassaway, Abhijeet Kapoor et al. · Journal of the American Chemical Society · 2016 · 296 citations · Full text

7-Hydroxymitragynine Is an Active Metabolite of Mitragynine and a Key Mediator of Its Analgesic Effects

Andrew C. Kruegel, Rajendra Uprety, Steven G. Grinnell et al. · ACS Central Science · 2019 · 197 citations · Full text

Truncated G protein-coupled mu opioid receptor MOR-1 splice variants are targets for highly potent opioid analgesics lacking side effects

Susruta Majumdar, Steven G. Grinnell, Valerie Le Rouzic et al. · Proceedings of the National Academy of Sciences · 2011 · 154 citations · Full text

Pain Medicine, Molecular Pain, Truncated Splice Variants +19