Steven G. Grinnell

Plasma proteomic associations with genetics and health in the UK Biobank

Benjamin B. Sun, Joshua Chiou, Matthew Traylor et al. · Nature · 2023 · 1.2K citations · Full text

Mitragynine/Corynantheidine Pseudoindoxyls As Opioid Analgesics with Mu Agonism and Delta Antagonism, Which Do Not Recruit β-Arrestin-2

András Váradi, Gina F. Marrone, Travis C. Palmer et al. · Journal of Medicinal Chemistry · 2016 · 297 citations · Full text

Pain Medicine, Mitragynine/corynantheidine Pseudoindoxyls, Pharmacotherapy +20

The Behavioral Effects of the Antidepressant Tianeptine Require the Mu-Opioid Receptor

Benjamin A. Samuels, Katherine M. Nautiyal, Andrew C. Kruegel et al. · Neuropsychopharmacology · 2017 · 266 citations · Full text

Psychotropic Medication, Psychopharmacology, Pharmacotherapy +17

7-Hydroxymitragynine Is an Active Metabolite of Mitragynine and a Key Mediator of Its Analgesic Effects

Andrew C. Kruegel, Rajendra Uprety, Steven G. Grinnell et al. · ACS Central Science · 2019 · 197 citations · Full text

Truncated G protein-coupled mu opioid receptor MOR-1 splice variants are targets for highly potent opioid analgesics lacking side effects

Susruta Majumdar, Steven G. Grinnell, Valerie Le Rouzic et al. · Proceedings of the National Academy of Sciences · 2011 · 154 citations · Full text

Pain Medicine, Molecular Pain, Truncated Splice Variants +19