Valerie Le Rouzic

Mitragynine/Corynantheidine Pseudoindoxyls As Opioid Analgesics with Mu Agonism and Delta Antagonism, Which Do Not Recruit β-Arrestin-2

András Váradi, Gina F. Marrone, Travis C. Palmer et al. · Journal of Medicinal Chemistry · 2016 · 297 citations · Full text

Pain Medicine, Mitragynine/corynantheidine Pseudoindoxyls, Pharmacotherapy +20

7-Hydroxymitragynine Is an Active Metabolite of Mitragynine and a Key Mediator of Its Analgesic Effects

Andrew C. Kruegel, Rajendra Uprety, Steven G. Grinnell et al. · ACS Central Science · 2019 · 197 citations · Full text

Truncated G protein-coupled mu opioid receptor MOR-1 splice variants are targets for highly potent opioid analgesics lacking side effects

Susruta Majumdar, Steven G. Grinnell, Valerie Le Rouzic et al. · Proceedings of the National Academy of Sciences · 2011 · 154 citations · Full text

Pain Medicine, Molecular Pain, Truncated Splice Variants +19

Pharmacological characterization of novel synthetic opioids (NSO) found in the recreational drug marketplace

Michael H. Baumann, Susruta Majumdar, Valerie Le Rouzic et al. · Neuropharmacology · 2017 · 90 citations

Opioid Epidemic, Substance Abuse, Pharmacological Characterization +13

Controlling opioid receptor functional selectivity by targeting distinct subpockets of the orthosteric site

Rajendra Uprety, Tao Che, Saheem A. Zaidi et al. · eLife · 2021 · 65 citations · Full text