Tao Che

Ultra-large library docking for discovering new chemotypes

Jiankun Lyu, Sheng Wang, Trent E. Balius et al. · Nature · 2019 · 947 citations

Targeted Library, Medicine, Natural Sciences +6

TRUPATH, an open-source biosensor platform for interrogating the GPCR transducerome

Reid H. J. Olsen, Jeffrey F. DiBerto, Justin G. English et al. · Nature Chemical Biology · 2020 · 531 citations · Full text

Engineering, Biochemistry, Bioanalysis +5

Structure of a Hallucinogen-Activated Gq-Coupled 5-HT2A Serotonin Receptor

Kuglae Kim, Tao Che, Ouliana Panova et al. · Cell · 2020 · 473 citations · Full text

Functional Selectivity, Medicine, Neurotransmitter +3

Structure of the D2 dopamine receptor bound to the atypical antipsychotic drug risperidone

Sheng Wang, Tao Che, Anat Levit et al. · Nature · 2018 · 454 citations · Full text

Molecular Pharmacology, Psychiatry, Medicine +6

Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor

Tao Che, Susruta Majumdar, Saheem A. Zaidi et al. · Cell · 2018 · 362 citations · Full text

Kappa Opioid Receptor, Molecular Pharmacology, Functional Selectivity +9