Concepedia

TRUPATH, an open-source biosensor platform for interrogating the GPCR transducerome

Reid H. J. Olsen, Jeffrey F. DiBerto, Justin G. English, Alexis M. Glaudin, B. Krumm, Samuel T. Slocum, Tao Che, Ariana C. Gavin, John D. McCorvy, Bryan L. Roth,

Nature Chemical Biology · 2020 · 569 citations · 40 references

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40

Switching of the coupling of the β2-adrenergic receptor to different G proteins by protein kinase A

Yehia Daaka, Louis M. Luttrell, Robert J. Lefkowitz · Nature · 1997 · 1.3K citations

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Structure-based discovery of opioid analgesics with reduced side effects

Aashish Manglik, Henry J. Lin, Dipendra K. Aryal et al. · Nature · 2016 · 946 citations · Full text

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Comparison of the pharmacology and signal transduction of the human cannabinoid CB1 and CB2 receptors.

Christian C. Felder, Kelly E. Joyce, Eileen M. Briley et al. · Molecular Pharmacology · 1995 · 879 citations

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Structure of RGS4 Bound to AlF4−-Activated Giα1: Stabilization of the Transition State for GTP Hydrolysis

J.J.G. Tesmer, David M. Berman, Alfred G. Gilman et al. · Cell · 1997 · 788 citations · Full text

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PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome

Wesley K. Kroeze, Maria F. Sassano, Xi‐Ping Huang et al. · Nature Structural & Molecular Biology · 2015 · 785 citations · Full text

, , +9