Concepedia

Alexander Flohr

AF

Statistics

Publications

13

Citations

930

H-Index

12

Active since

1998

Affiliations

Roche (Switzerland)(Current)

Scripps Research Institute

La Roche College

Alexander Flohr is an author at Roche (Switzerland) specializing in life sciences, pharmacology, and enzyme inhibition.

Publications per year

1998–2022

13

Publications

13

Scaffold hopping

Hans‐Joachim Böhm, Alexander Flohr, Martin Ståhl · Drug Discovery Today Technologies · 2004 · 335 citations

Preclinical Profile of a Potent γ-Secretase Inhibitor Targeting Notch Signaling with <i>In vivo</i> Efficacy and Pharmacodynamic Properties

Leopoldo Luistro, Wei He, Melissa Smith et al. · Cancer Research · 2009 · 191 citations · Full text

Medicine, Oncology, Pharmacology +16

Generation of Aβ38 and Aβ42 Is Independently and Differentially Affected by Familial Alzheimer Disease-associated Presenilin Mutations and γ-Secretase Modulation

Richard Page, Karlheinz Baumann, Masanori Tomioka et al. · Journal of Biological Chemistry · 2007 · 163 citations · Full text

Life Sciences, Biochemistry, Neuroscience +17

An Antibody-Catalyzed Allylic Sulfoxide−Sulfenate Rearrangement

Zhaohui Sunny Zhou, Alexander Flohr, Donald Hilvert · The Journal of Organic Chemistry · 1999 · 38 citations

Life Sciences, Biochemistry, Chemistry +12

A high quality, industrial data set for binding affinity prediction: performance comparison in different early drug discovery scenarios

Andreas Tosstorff, M.G. Rudolph, Jason C. Cole et al. · Journal of Computer-Aided Molecular Design · 2022 · 31 citations · Full text

Pharmacy, Bioinformatics, Medicinal Chemistry +17

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