Melissa Smith

Preclinical Profile of a Potent γ-Secretase Inhibitor Targeting Notch Signaling with <i>In vivo</i> Efficacy and Pharmacodynamic Properties

Leopoldo Luistro, Wei He, Melissa Smith et al. · Cancer Research · 2009 · 188 citations · Full text

Ro4929097 Ic50, Cancer Biology, Tumor Biology +17

Effects of N‐acetylcysteine on glutathione oxidation and fatigue during handgrip exercise

Yves Matuszczak, Jeffrey A. Jones, Samme Lansdowne et al. · Muscle & Nerve · 2005 · 144 citations

Physical Activity, Glutathione Homeostasis, Handgrip Exercise +17

Discovery of [4-Amino-2-(1-methanesulfonylpiperidin-4-ylamino)pyrimidin-5-yl](2,3-difluoro-6- methoxyphenyl)methanone (R547), A Potent and Selective Cyclin-Dependent Kinase Inhibitor with Significant in Vivo Antitumor Activity

Xin‐Jie Chu, Wanda DePinto, David Bartkovitz et al. · Journal of Medicinal Chemistry · 2006 · 116 citations · Full text

Drug Target, Pharmacotherapy, Cell Cycle +17

<i>In vitro</i> and <i>in vivo</i> activity of R547: a potent and selective cyclin-dependent kinase inhibitor currently in phase I clinical trials

Wanda DePinto, Xin‐Jie Chu, Xuefeng Yin et al. · Molecular Cancer Therapeutics · 2006 · 102 citations · Full text

Molecular Pharmacology, Tumor Biology, Cell Cycle Block +15

In Vivo Transfer of Intracellular Labels from Locally Implanted Bone Marrow Stromal Cells to Resident Tissue Macrophages

Edyta Pawelczyk, Elaine Jordan, Arun Balakumaran et al. · PLoS ONE · 2009 · 90 citations · Full text

Cell Therapy, Engineering, Harvested Plaques +16